Scientific Publications

• Home
• About Us
• Scientific Publications

About Us

Publications & Presentations Resulting from Work at ORB

Blue arrow indicates ORB employee is a co-author. For all other publications, Ocean Ridge Biosciences is cited as service provider in methods section.

Published:

1. Ricci M, Xu Y, Hammond HL, Willoughby DA, Nathanson L, Rodriguez MM, Vatta M, Lipshultz SE, Lincoln J. Myocardial alternative RNA splicing and gene expression profiling in early stage hypoplastic left heart syndrome. PLoS One. 2012;7(1):e29784. Epub 2012 Jan 27. PubMed PMID: 22299024.
2. Miller BH, Zeier Z, Xi L, Lanz TA, Deng S, Strathmann J, Willoughby D, Kenny PJ, Elsworth JD, Lawrence MS, Roth RH, Edbauer D, Kleimand RJ, Wahlestedt C. MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function. PNAS, 2012 Jan 11.
3. Wallace AM, Hardigan A, Geraghty P, Salim S, Gaffney A, Thankachen J, Arellanos L, D'Armiento JM, Foronjy RF. Protein Phosphatase 2a (Pp2a) Regulates Innate Immune and Proteolytic Responses to Cigarette Smoke Exposure in the Lung. Toxicol Sci. 2012 Jan 5. [Epub ahead of print] PubMed PMID: 22223484.
4. Wang H, Bian S, Yang CS. Green tea polyphenol EGCG suppresses lung cancer cell growth through upregulating miR-210 expression caused by stabilizing HIF-1{alpha}. Carcinogenesis. 2011 Dec; 32(12):1881-9. PubMed PMID: 21965273.
5. Kocerha J, Kouri N, Baker M, Finch N, DeJesus-Hernandez M, Gonzalez J, Chidamparam K, Josephs KA, Boeve BF,Graff-Radford NR, Crook J, Dickson DW, Rademakers R. Altered microRNA expression in frontotemporal lobar degeneration with TDP-43 pathology caused by progranulin mutations. BMC Genomics. 2011 Oct 27;12:527. PubMed PMID: 22032330.
6. Gowda M, Godder K, Kmieciak M, Worschech A, Ascierto ML, Wang E, Marincola FM, Manjili MH. Distinct signatures of the immune responses in low risk versus high risk neuroblastoma. J Transl Med. 2011 Oct 6;9:170. PubMed PMID: 21978632.
7. Drosatos K, Drosatos-Tampakaki Z, Khan R, Homma S, Schulze PC, Zannis VI, Goldberg IJ. Inhibition of c-Jun-N-terminal kinase increases cardiac peroxisome proliferator-activated receptor alpha expression and fatty acid oxidation and prevents lipopolysaccharide-induced heart dysfunction. J Biol Chem. 2011 Oct 21;286(42):36331-9. Epub 2011 Aug 26. PubMed PMID: 21873422.
8. Lemaître V, Dabo AJ, D'Armiento J. Cigarette smoke components induce matrix metalloproteinase-1 in aortic endothelial cells through inhibition of mTOR signaling. Toxicol Sci. 2011 Oct;123(2):542-9. Epub 2011 Jul 8. PubMed PMID:21742783.
9. Enquobahrie DA, Abetew DF, Sorensen TK, Willoughby D, Chidambaram K, Williams MA. (2011) Placental microRNA expression in pregnancies complicated by preeclampsia. Am J Obstet Gynecol. 204(2):178.e12-21, PMID: 21093846.
10. Mayor-Lynn K, Toloubeydokhti T, Cruz AC, Chegini N. (2011) Expression profile of microRNAs and mRNAs in human placentas from pregnancies complicated by preeclampsia and preterm labor. Reprod Sci. 18:46-56. PMID: 21079238.
11. Surgucheva I, Chidambaram K., Willoughby DA, and Surguchov A. (2010) Matrix metalloproteinase 9 expression: new regulatory elements. Journal of Ocular Biology, Disease, and Informatics. DOI: 10.1007/s12177-010-9054-2.
12. Son N-H, Yu S, Tuinei J, Arai K, Hamai, H, Homma, S, Shulman, GI, Abel, ED, and Goldberg IJ. (2010) PPARγ-induced cardiolipotoxicity in mice is ameliorated by PPARα deficiency despite increases in fatty acid oxidation. J. Clinical Invest. 120:3443-54. PMID: 20852389.
13. Rappa G, Anzanello F, Lorico A. (2010) Imatinib mesylate enhances the malignant behavior of human breast carcinoma cells. Cancer Chemother Pharmacol. 67:919-26. PMID: 20596710.
14. Hollander JA, Im H, Amelio AL, Kocerha J, Bali P, Lu Q, Willoughby D, Wahlestedt C, Conkright MD, & Kenny PJ. (2010) Striatal microRNA controls cocaine intake through CREB signalling. Nature 466:197-202. PMID: 20613834.
15. Khorram O, Han G, Bagherpour R, Magee TR, Desai M, Ross MG, Chaudhri AA, Toloubeydokhti T, and Pearce WJ. (2010) Effect of maternal undernutrition on vascular expression of micro and messenger RNA in newborn and aging offspring. Am. J. Physiol. Regul. Integr. Comp. Physiol. 298: R1366-R1374. PMID: 20200130.
16. Rappa G, and Lorico A. (2010) Phenotypic characterization of mammosphere-forming cells from the human MA-11 breast carcinoma cell line. Experimental Cell Research 316:1576-86. PMID: 20074564.
17. D’Armiento JM, et al. (2009) Eosinophil and T cell markers predict functional decline in COPD patients. Respiratory Research 10:113. PMID: 19925666.
18. Kocerha J, Faghihi MA, Lopez-Toledano MA, Huang J, Ramsey AJ, Caron MG, Sales N, Willoughby D, Elmen J, Hansen HF, Orum H, Kauppinen S, Kenny PJ, Wahlestedt C. (2009) "MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction" PNAS, 106:3507-12. PMID: 19196972.
19. Rabinowits G, Gerçel-Taylor C, Day JM, Taylor DD, Kloecker GH. (2009) Exosomal microRNA: a diagnostic marker for lung cancer. Clin Lung Cancer. 10:42-6. PMID: 19289371.
20. Rappa G, Fodstad O, and Lorico A, (2008) The stem cell-associated antigen CD133 (Prominin-1) is a Molecular Therapeutic Target for Metastatic Melanoma. Stem Cells, 26:3008-17. PMID: 18802032.
21. Taylor DD, Gercel-Taylor C. (2008) MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Gynecologic Oncology 110:13–21. PMID: 18589210.
22. Seigel GM, Hackam AS, Ganguly A, Mandell LM, and Gonzalez-Fernandez, F. (2007) Human embryonic and neuronal stem cell markers in retinoblastoma. Molecular Vision, 13:823-832. PMID: 17615543.

Abstracts:

1. Miller, B. H., Willoughby, D., Kenny, P. J., and Wahlestedt, C. (2009) "MicroRNA dysregulation in schizophrenia and bipolar disorder reveals novel gene networks involved in disease" Keystone Symposia: The Molecular Basis of Schizophrenia & Bipolar Disorder, Keystone, CO.
2. Coito,C., Kota,S., Willoughby, D., Tellinghuisen, T., and Strosberg, D., (2008), "Differences in susceptibility to interferon of infectious HCV genotype 1b and 2a grown in Huh-7.5 hepatoma cells" 15th International Symposium on Hepatitis C Virus and related viruses, San Antonio, TX
3. Coito,C., Kota,S., Willoughby, D., Tellinghuisen, T., and Strosberg, D., (2007) "Production of infectious genotype 1b Hepatitis C Virus in human hepatoma cells" 58th Annual Meeting of the American Association for the Study of Liver Diseases, Boston, MA